Specificity of autoantibodies in autoimmune thrombocytopenia

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Specificity of autoantibodies in autoimmune thrombocytopenia.

In 42 patients with autoimmune thrombocytopenia (AITP) and a positive direct platelet suspension immunofluorescence test (PSIFT), the antigenic specificity of the autoantibodies was studied. Because the autoantibodies were often not detectable in the serum and additional HLA antibodies may disturb the reaction pattern with the platelet panel, we used eluates prepared from the patients' platelet...

متن کامل

Autoantibodies in systemic autoimmune diseases: specificity and pathogenicity.

In this Review we focus on the initiation of autoantibody production and autoantibody pathogenicity, with a special emphasis on the targeted antigens. Release of intracellular antigens due to excessive cell death or to ineffective clearance of apoptotic debris, modification of self-antigens during inflammatory responses, and molecular mimicry contribute to the initiation of autoantibody product...

متن کامل

Autoantibodies in systemic autoimmune diseases : specificity and pathogenicity

Introduction The first autoantibodies were discovered in the late 1940s, when both antinuclear antibodies (ANAs) and rheumatoid factors (RFs) were described as serum factors that could bind nuclear antigens and immunoglobulins, respectively (1, 2). ANA and RF were recognized as diagnostic features of systemic lupus erythematosus (SLE) or RA, respectively, and as contributors to disease pathogen...

متن کامل

Autoantibodies in Autoimmune Pancreatitis

Autoimmune pancreatitis (AIP) was first used to describe cases of pancreatitis with narrowing of the pancreatic duct, enlargement of the pancreas, hyper-γ-globulinaemia, and antinuclear antibody (ANA) positivity serologically. The main differential diagnosis, is pancreatic cancer, which can be ruled out through radiological, serological, and histological investigations. The targets of ANA in pa...

متن کامل

Autoantibodies in Systemic Autoimmune Disorders

1 INOVA Diagnostics, Inc., 9900 Old Grove Road, San Diego, CA 92131-1638, USA 2Antiphospholipid Standardization Laboratory, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX 77555, USA 3 Laboratorio di Ricerche in Immunoreumatologia, Università di Milano, Istituto Auxologico Italiano, 20095 Cusano Milanino, Italy 4 Faculty of Medicine, ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Blood

سال: 1982

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v59.1.23.bloodjournal59123